Described herein are novel methods of preparing a compound of Formula II or a pharmaceutically acceptable salt thereof. In some embodiments, the method is for preparing betrixaban or a pharmaceutically acceptable salt thereof. Also described are compositions comprising substantially pure betrixaban free base or salt thereof.
申请公布号
EP2513058(A1)
申请公布日期
2012.10.24
申请号
EP20100801495
申请日期
2010.12.15
申请人
MILLENNIUM PHARMACEUTICALS, INC.;PORTOLA PHARMACEUTICALS, INC.