摘要 |
<p>The present invention relates to improved methods to detect and/or investigate the interaction between an analyte ligand and a cell or cell-like particle. Such methods use, in a particular way, a particular mass-sensitive chemical sensor comprising a surface acoustic wave device, to detect a particular property of an acoustic wave stimulated on the surface of such detector. The methods of the present invention are flexible and easy to perform, and can be used for example, to detect and investigate antibody interaction to extra-cellular domains of membrane proteins presented on intact mammalian cells.</p> |