| 发明名称 |
COMPOSITIONS AND METHODS OF TOLERIZING A PRIMATE TO AN ANTIGEN |
| 摘要 |
<p>Inducing tolerance in a primate by use of a compound, or a combination of at least two compounds, that has certain characteristics when tested in vitro. The compound, alone or in combination, is preferably TRX1 antibody and the compound or combination is preferably used in accordance with a specified dosing regimen.</p> |
| 申请公布号 |
EP1587541(B8) |
申请公布日期 |
2012.10.24 |
| 申请号 |
EP20040706089 |
申请日期 |
2004.01.28 |
| 申请人 |
ISIS INNOVATION LIMITED;CAMBRIDGE ENTERPRISE LIMITED |
发明人 |
FREWIN, MARK;WALDMANN, HERMAN;GORMAN, SCOTT;HALE, GEOFF;RAO, PATRICIA;KORNAGA, TADEUSZ;RINGLER, DOUGLAS;COBBOLD, STEPHEN;WINSOR-HINES, DAWN |
| 分类号 |
A61K39/395;C12N15/09;A61K45/00;A61K45/06;A61P37/00;A61P37/06;A61P43/00;C07K;C07K14/73;C07K16/00;C07K16/28;C07K16/46;C12N15/13;C12P21/08;C12Q1/02;G01N33/50 |
主分类号 |
A61K39/395 |
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