发明名称 |
MEAN DNA COPY NUMBER OF CHROMOSOMAL REGIONS IS OF PROGNOSTIC SIGNIFICANCE IN CANCER |
摘要 |
Methods for predicting a disease free time interval (DFI) for a cancer patient under consideration for initial or further chemotherapy treatment are disclosed. The methods include obtaining a biological sample from a patient and detecting a copy number of chromosome region A1 and/or C2. The mean copy number per cell is correlated with a DFI for the subject. The chemotherapy can include doxorubicin and/or L-asparaginase treatment. Also provided are kits for predicting DFI in a subject with cancer and computer readable storage media for performing the presently disclosed methods. |
申请公布号 |
EP2513340(A1) |
申请公布日期 |
2012.10.24 |
申请号 |
EP20100861217 |
申请日期 |
2010.12.14 |
申请人 |
NORTH CAROLINA STATE UNIVERSITY |
发明人 |
BREEN, MATTHEW |
分类号 |
C12Q1/68;G01N33/50 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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