发明名称 |
Melting curve analysis with exponential background subtraction |
摘要 |
A method for clustering melting profiles of a plurality of nucleic acid samples, comprising measuring the fluorescence of each nucleic acid sample as a function of temperature to produce a respective raw melting curve for each respective nucleic acid sample, and clustering genotypes of the plurality of nucleic acid samples to form a plurality of clusters of melting curves. A system for analyzing a plurality of nucleic acid samples comprising an instrument for sequentially heating fluorescently detectable complexes while monitoring their fluorescence, a central processing unit (CPU) for performing computer executable instructions, and a memory storage device for storing computer executable instructions that when executed by the CPU cause the CPU to cluster genotypes of a plurality of nucleic acid samples.
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申请公布号 |
US8296074(B2) |
申请公布日期 |
2012.10.23 |
申请号 |
US201113271764 |
申请日期 |
2011.10.12 |
申请人 |
PALAIS ROBERT ANDREW;WITTER CARL THOMAS;UNIVERSITY OF UTAH RESEARCH FOUNDATION |
发明人 |
PALAIS ROBERT ANDREW;WITTER CARL THOMAS |
分类号 |
G06F19/00;C12Q1/68;G06F15/00 |
主分类号 |
G06F19/00 |
代理机构 |
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地址 |
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