| 发明名称 |
COMPOSITIONS COMPRISING MODIFIED LCAT AND USE THEREOF FOR TREATING ATHEROSCLEROSIS |
| 摘要 |
The invention provides compounds, pharmaceutical compositions and methods for treating atherosclerosis, inflammation, thrombosis and other conditions and for decreasing or prevention of accumulation of cholesterol in a subject by modifying LCAT polypeptide.
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| 申请公布号 |
CA2654661(C) |
申请公布日期 |
2012.10.23 |
| 申请号 |
CA20072654661 |
申请日期 |
2007.06.26 |
| 申请人 |
AMGEN INC. |
发明人 |
KAYSER, FRANK;LABELLE, MARC;SHAN, BEI;ZHANG, JIAN;ZHOU, MINGYUE |
| 分类号 |
A61K31/497;A61P9/10 |
主分类号 |
A61K31/497 |
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