发明名称 |
Method for producing 6-hydroxyethylpenam compound |
摘要 |
The present invention provides a method by which a 6-hydroxyethyl penam compound represented by General Formula (2) below can be produced with a high selectivity: wherein R represents a hydrogen atom or a protective group for carboxylic acid and X2 represents a halogen atom; the method including the steps of reacting a Grignard reagent with a halogeno penam compound represented by General Formula (1) below: wherein R and X2 are the same as above, and X1 represents a halogen atom; reacting the generated compound with an amine compound; and further reacting the generated compound with acetaldehyde. |
申请公布号 |
US8293893(B2) |
申请公布日期 |
2012.10.23 |
申请号 |
US20080530307 |
申请日期 |
2008.03.06 |
申请人 |
TANAKA HIDEO;KUROBOSHI MANABU;TATEYAMA SYOICHI;YAMADA TAKAE;KAMEYAMA YUTAKA;OTSUKA CHEMICAL CO., LTD. |
发明人 |
TANAKA HIDEO;KUROBOSHI MANABU;TATEYAMA SYOICHI;YAMADA TAKAE;KAMEYAMA YUTAKA |
分类号 |
C07D499/04;C07D499/861 |
主分类号 |
C07D499/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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