发明名称 Process for the preparation of compositions for modulating a kinase cascade and methods of use thereof
摘要 The invention relates to compositions comprising 2-(5-(4-(2-morpholinoethoxy)phenyl)pyridin-2-yl)-N-benzylacetamide and its mesylate and dihydrochloride salts. More specifically, the invention provides an efficient process for the synthesis of 2-(5-(4-(2-morpholinoethoxy) phenyl)pyridin-2-yl)-N-benzylacetamide and its mesylate and dihydrochloride salts and methods for modulating one or more components of a kinase cascade using the compositions of the invention.
申请公布号 US8293739(B2) 申请公布日期 2012.10.23
申请号 US201113094667 申请日期 2011.04.26
申请人 HANGAUER, JR. DAVID G.;COUGHLIN DANIEL;GALE JONATHAN;CODY JEREMY A.;PATRA DEBASIS;PALMER GRANT J.;ISBESTER PAUL K.;SALSBURY JONATHON;KINEX PHARMACEUTICALS, LLC 发明人 HANGAUER, JR. DAVID G.;COUGHLIN DANIEL;GALE JONATHAN;CODY JEREMY A.;PATRA DEBASIS;PALMER GRANT J.;ISBESTER PAUL K.;SALSBURY JONATHON
分类号 A61K31/535 主分类号 A61K31/535
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