| 摘要 |
FIELD: chemistry. ^ SUBSTANCE: invention relates to a method of producing a compound of formula (V) which can be used in pharmaceutical industry . The method involves reaction of a compound of formula (II) with a compound of formula (III) in the presence of a titanium salt of formula Ti(Hal)n(OR)4-n, where Hal is a halogen radical, n equals 0, 1, 2 or 3, R is an alkyl or arylalkyl, and subsequent reaction of the reaction product with an alcohol of formula (IV), where R1 and R2 denote alkyl or arylalkyl, where the aryl is phenyl or naphthyl. ^ EFFECT: novel efficient method of producing compounds of the given formula using novel intermediate compounds is disclosed. ^ 16 cl, 9 ex |
