| 摘要 |
FIELD: medicine. ^ SUBSTANCE: invention refers to medicine, particularly to methods for preparing 68Ga solutions which involves the following stages: reaction of 68Ge/68Ga generator eluate and cation-exchange resin, washing of cation-exchange resin in the mixture of 0.2-1 M hydrochloric acid and 20-80 vol. % of acetone, eluation of 68Ga with cation-exchange resin by the mixture of 1.8-2.5 M hydrochloric acid and 20-80 vol. % of acetone, reaction of the prepared eluate and anion-exchange resin, washing of anion-exchange resin in an organic solvent, drying of anion-exchange resin by air and neutral gas and eluation of 68Ga with anion-exchange resin by an aqueous solution of 0.01-0.1 M hydrochloric acid wherein it's amount is 15-25 less than that of the initial 68Ge/68Ga generator eluate. EFFECT: method provides preparing the concentrated solutions of the 68Ga radionuclides of high chemical and radiochemical purity containing no organic solvents that enables preparing the 68Ga radiopharmaceutical of high molar activity and radiochemical purity. ^ 2 cl, 3 tbl, 2 dwg, 4 ex |
