发明名称 |
NANOPORE-BASED SINGLE DNA MOLECULE CHARACTERIZATION, IDENTIFICATION AND ISOLATION USING SPEED BUMPS |
摘要 |
The present invention relates to a method of using nanopores to obtain sequence information of sample DNAs in ss test DNAs. The method comprises using speed bumps to stall the ss test DNAs in the nanopores at random positions of the ss test DNAs to obtain sequence information of each and every nucleotides of the sample DNAs, and to construct the whole sequences of the sample DNAs. The present invention also relates to identification and/or isolation of test DNAs having desired sequence(s) using nanopore detectors facilitated by speed bump. |
申请公布号 |
WO2012088341(A3) |
申请公布日期 |
2012.10.18 |
申请号 |
WO2011US66632 |
申请日期 |
2011.12.21 |
申请人 |
GENIA TECHNOLOGIES, INC.;DAVIS, RANDY;CHEN, ROGER |
发明人 |
DAVIS, RANDY;CHEN, ROGER |
分类号 |
C12Q1/68;B82Y10/00;G01N27/26 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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