| 发明名称 |
TREATMENT OF NUCLEAR RESPIRATORY FACTOR 1 (NRF1) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO NRF1 |
| 摘要 |
The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Nuclear Respiratory Factor 1 (NRF1), in particular, by targeting natural antisense polynucleotides of Nuclear Respiratory Factor 1 (NRF1). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of NRF1.
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| 申请公布号 |
US2012264812(A1) |
申请公布日期 |
2012.10.18 |
| 申请号 |
US201013518250 |
申请日期 |
2010.12.29 |
| 申请人 |
COLLARD JOSEPH;KHORKOVA SHERMAN OLGA;CURNA, INC. |
发明人 |
COLLARD JOSEPH;KHORKOVA SHERMAN OLGA |
| 分类号 |
A61K31/713;A61P3/10;A61P5/48;A61P9/10;A61P25/00;A61P25/16;A61P25/28;A61P35/00;A61P37/00;C07H21/02;C12N5/071;G01N25/04 |
主分类号 |
A61K31/713 |
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