摘要 |
A process is described for the preparation of drospirenone, a synthetic steroid with progestogenic, antimineralocorticoid and antiandrogenic activity, useful for preparing pharmaceutical compositions with contraceptive action; comprising the oxidation of 17α-(3-hydroxypropyl)-6&bgr;,7&bgr;,15&bgr;,16&bgr;-dimethylene-5&bgr;-androstane-3&bgr;,5,17&bgr;-triol. |