发明名称 |
Glycosylated Form of Antigenic GLP-1 Analogue |
摘要 |
Disclosed is a glucagon-like peptide-1 (GLP-1) analogue which is obtained by ameliorating a highly antigenic GLP-1 analogue so that the GLP-1 analogue has reduced antigenicity without being lowered in the blood glucose suppressing activity. Specifically disclosed is a glycosylated form of an antigenic GLP-1 analogue, which has GLP-1 activity and is obtained by substituting at least one amino acid of an antigenic GLP-1 analogue with a glycosylated amino acid. |
申请公布号 |
US2012264684(A1) |
申请公布日期 |
2012.10.18 |
申请号 |
US201013502723 |
申请日期 |
2010.10.25 |
申请人 |
KAJIHARA YASUHIRO;TSUJI TAKASHI;NAMBU YURI;ISHII KAZUYUKI;YOSHIDA KENTA;TEZUKA KATSUNARI |
发明人 |
KAJIHARA YASUHIRO;TSUJI TAKASHI;NAMBU YURI;ISHII KAZUYUKI;YOSHIDA KENTA;TEZUKA KATSUNARI |
分类号 |
C07K14/605;A61K38/26;A61P3/10 |
主分类号 |
C07K14/605 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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