发明名称 Combinations Comprising Heterocyclic Inhibitors of MEK and Methods of Use Thereof
摘要 Disclosed are combinations comprising (a) a compound of the Formula: wherein R1, R2, R7, R8, R9 and W are as defined in the specification, and (b) at least one additional therapeutic agent. Such combinations are useful in the treatment of hyperproliferative diseases, such as cancer and inflammation, and inflammatory conditions in mammals. Also disclosed are methods of using such combinations in the treatment of hyperproliferative diseases and inflammatory conditions in mammals.
申请公布号 US2012263679(A1) 申请公布日期 2012.10.18
申请号 US201213484093 申请日期 2012.05.30
申请人 MARLOW ALLISON L.;WALLACE ELI;SEO JEONGBEOB;LYSSIKATOS JOSEPH P.;YANG HONG WOON;BLAKE JAMES;ARRAY BIOPHARMA INC. 发明人 MARLOW ALLISON L.;WALLACE ELI;SEO JEONGBEOB;LYSSIKATOS JOSEPH P.;YANG HONG WOON;BLAKE JAMES
分类号 A61K31/4412;A61K31/4439;A61K31/4704;A61K31/501;A61K31/655;A61K31/7088;A61K38/17;A61K38/21;A61K39/395;A61K48/00;A61P5/28;A61P9/00;A61P31/04;A61P35/00;A61P37/00;C07D213/80;C07D213/82;C07D237/24;C07D401/04;C07D401/06;C07D413/02;C07D413/04;C07D413/14;C07D417/02;C07D417/04;C07D471/04 主分类号 A61K31/4412
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