发明名称 |
Combinations Comprising Heterocyclic Inhibitors of MEK and Methods of Use Thereof |
摘要 |
Disclosed are combinations comprising (a) a compound of the Formula: wherein R1, R2, R7, R8, R9 and W are as defined in the specification, and (b) at least one additional therapeutic agent. Such combinations are useful in the treatment of hyperproliferative diseases, such as cancer and inflammation, and inflammatory conditions in mammals. Also disclosed are methods of using such combinations in the treatment of hyperproliferative diseases and inflammatory conditions in mammals. |
申请公布号 |
US2012263679(A1) |
申请公布日期 |
2012.10.18 |
申请号 |
US201213484093 |
申请日期 |
2012.05.30 |
申请人 |
MARLOW ALLISON L.;WALLACE ELI;SEO JEONGBEOB;LYSSIKATOS JOSEPH P.;YANG HONG WOON;BLAKE JAMES;ARRAY BIOPHARMA INC. |
发明人 |
MARLOW ALLISON L.;WALLACE ELI;SEO JEONGBEOB;LYSSIKATOS JOSEPH P.;YANG HONG WOON;BLAKE JAMES |
分类号 |
A61K31/4412;A61K31/4439;A61K31/4704;A61K31/501;A61K31/655;A61K31/7088;A61K38/17;A61K38/21;A61K39/395;A61K48/00;A61P5/28;A61P9/00;A61P31/04;A61P35/00;A61P37/00;C07D213/80;C07D213/82;C07D237/24;C07D401/04;C07D401/06;C07D413/02;C07D413/04;C07D413/14;C07D417/02;C07D417/04;C07D471/04 |
主分类号 |
A61K31/4412 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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