USE OF THE COMBINATORIAL DIVERSITY OF T-LYMPHOCYTE REPERTOIRE AS A PROGNOSTIC MARKER OF CANCER

摘要

Method for ex vivo or in vitro prognosis of an individual suffering from a solid cancer, comprises: (i) measuring the level of diversity of T cell repertoire of the individual by nucleic acid from a biological sample containing white cells of the individual; (ii) comparing the level of diversity measured in step (i) with a predetermined threshold; and (iii) deducing, if the level of diversity measured in step (i) is below the predetermined threshold, the individual having a high risk of early death.