The present invention relates to proteases having at least 75% identity to a protease derived from Thermoascus aurantiacus and comprises at least one modification in the amino acid sequence thereof. These protease variants have improved thermostability. The invention also relates to DNA encoding these proteases, methods of their production, as well as the use thereof.
申请公布号
EP2510093(A2)
申请公布日期
2012.10.17
申请号
EP20100803307
申请日期
2010.12.10
申请人
NOVOZYMES A/S;NOVOZYMES NORTH AMERICA, INC.
发明人
MATSUI, TOMOKO;NOERGAARD, ALLAN;POULSEN, THOMAS, AGERSTEN;MATTHEWS, JOHN