发明名称 |
METHODS OF FACILITATING NEURAL CELL SURVIVAL USING GDNF FAMILY LIGAND (GFL) MIMETICS OR RET SIGNALING PATHWAY ACTIVATORS |
摘要 |
<p>Disclosed are compounds and methods for treating neurological and other disorders by administering to a subject in need thereof an effective amount of a compound having binding and/or modulation specificity for GFRαreceptor molecules, which can be mimetics of glial-derived neurotrophic factor (GDNF) family ligands (GFLs), GFRα/RET signaling pathway agonists, and/or direct RET agonists (activators).</p> |
申请公布号 |
EP2509953(A2) |
申请公布日期 |
2012.10.17 |
申请号 |
EP20100790954 |
申请日期 |
2010.12.13 |
申请人 |
GENECODE AS |
发明人 |
SAARMA, MART;KARELSON, MATI;BESPALOV, MAXIM;PILV, MEHIS |
分类号 |
C07D215/46;A61K31/4706;A61K31/473;A61P25/28;C07D219/10;C07D263/57;C07D285/135;C07D295/192;C07D513/10 |
主分类号 |
C07D215/46 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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