发明名称 |
DRUG DELIVERY SYSTEM |
摘要 |
The subject invention provides a drug delivery system comprising at least one compartment consisting of (i) a drug-loaded thermoplastic polymer core, (ii) a drug-loaded thermoplastic polymer intermediate layer and (iii) a non-medicated thermoplastic polymer skin covering the intermediate layer, wherein said intermediate layer is loaded with (a) crystals of a first pharmaceutically active compound and with (b) a second pharmaceutically active compound in dissolved form and wherein said core is loaded with said second compound in dissolved form. |
申请公布号 |
EP1631255(B1) |
申请公布日期 |
2012.10.17 |
申请号 |
EP20040741599 |
申请日期 |
2004.05.19 |
申请人 |
MSD OSS B.V. |
发明人 |
GROENEWEGEN, RUDOLF, JOHANNES, JOSEPH;DE GRAAFF, WOUTER;OUT, HENK, JAN |
分类号 |
A61K9/00;A61K9/24;A61K31/565;A61K45/06;A61P15/18;A61P31/18 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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