发明名称 METHODS AND LOW DOSE REGIMENS FOR TREATING RED BLOOD CELL DISORDERS
摘要 <p>Disclosed herein are methods and low dose regimens for increasing fetal hemoglobin levels in patients with red blood cell disorders, such as beta thalassemia, sickle cell disease, other anemias, or blood loss. Fetal and total hemoglobin levels and red blood cell counts are increased by administering 2,2-dimethylbutyrate (DMB) alone or in combination with hydroxyurea, decitabine or an HDAC inhibitor. Treatment can be continued for at least two weeks.</p>
申请公布号 EP2509418(A1) 申请公布日期 2012.10.17
申请号 EP20100836658 申请日期 2010.12.08
申请人 HEMAQUEST PHARMACEUTICALS, INC.;TRUSTEES OF BOSTON UNIVERSITY 发明人 PERRINE, SUSAN;BERENSON, RONALD, J.;FALLER, DOUGLAS, V.
分类号 A01N37/10;A61K31/185;A61P7/00 主分类号 A01N37/10
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