发明名称 BIS-ACYLATED HYDROXYLAMINE DERIVATIVES
摘要 The invention provides certain bis-acylated hydroxylamine derivative compounds, pharmaceutical compositions and kits comprising such compounds, and methods of using such compounds or pharmaceutical compositions. In particular, the invention provides methods of using such compounds or pharmaceutical compositions for treating, preventing, or delaying the onset and/or develop of a disease or condition. In some embodiments, the disease or condition is selected from cardiovascular diseases, ischemia, reperfusion injury, cancerous disease, pulmonary hypertension and conditions responsive to nitroxyl therapy.
申请公布号 EP2509942(A2) 申请公布日期 2012.10.17
申请号 EP20100795136 申请日期 2010.12.07
申请人 JOHNS HOPKINS UNIVERSITY;CARDIOXYL PHARMACEUTICALS INC. 发明人 TOSCANO, JOHN P.;SUTTON, ART;KALISH, VINCENT J.;BROOKFIELD, FREDERICK ARTHUR;COURTNEY, STEPHEN MARTIN;FROST, LISA MARIE
分类号 C07C311/48;A61K31/18;A61K31/67;A61P9/04;C07C233/66;C07C233/92 主分类号 C07C311/48
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