| 发明名称 |
TGR5 AGONISTS |
| 摘要 |
<p>TGR5 agonists of structural formula VIII(Q), wherein X, R1, R2, and R5 are defined in the specification, pharmaceutically acceptable salts thereof, compositions thereof, and use of the compounds and compositions for treating diseases. The invention also comprises use of the compounds in and for the manufacture of medicaments, particularly for treating diseases.</p> |
| 申请公布号 |
EP2509960(A1) |
申请公布日期 |
2012.10.17 |
| 申请号 |
EP20100747545 |
申请日期 |
2010.08.11 |
| 申请人 |
EXELIXIS, INC. |
发明人 |
BOLLU, VENKATAIAH;BOREN, BRANT, CLAYTON;DALGARD, JACKLINE;FLATT, BRENTON, T.;HAQ, NADIA;HUDSON, SARAH;MOHAN, RAJU;MORRISSEY, MICHAEL;PRATT, BENJAMIN |
| 分类号 |
C07D233/64;A61K31/4164;A61K31/4178;A61K31/4439;A61K31/454;A61K31/496;A61P3/04;C07D233/84;C07D403/12 |
主分类号 |
C07D233/64 |
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