SENSITIVE MRI CONTRAST NANO AGENTS BASED IONIC COMPLEX CONTAINING ANIONIC AND CATIONIC POLYMER AND PREPARING METHOD THEREOF

摘要

PURPOSE: A nanocomposite containing anionic and cationic polymers and a method for preparing the same are provided to generate synergistic effect of amplifying magnetic resonance signal. CONSTITUTION: A method for fabricating a nanoparticle composite in which a magnetic resonance nano contrast agent is encapsulated in a polymer composite comprises: a step of mixing a contrast agent-containing organic solvent solution with anionic polymer-containing organic solvent solution to prepare an anionic polymer/magnetic resonance imaging nano contrast composite; and a step of adding cationic polymers to the composite.