发明名称 |
Formation of hydrogel in the presence of peroxidase and low concentration of hydrogen peroxide |
摘要 |
In a process of forming a hydrogel from a mixture comprising hydrogen peroxide (H2O2), horseradish peroxidase (HRP), and a polymer comprising a crosslinkable phenol group, the gelation rate in the solution and the crosslinking density in the hydrogel can be independently adjusted or controlled by selection of the molarity of H2O2 and concentration of HRP in the solution when the molarity of H2O2 is limited to be within a range and the concentration of HRP is limited to be above a threshold. A method for determining the range and threshold is disclosed. The hydrogel may be used to grow cells, in which case, the molarity of H2O2 may be selected to affect the differentiation or growth rate of the cells in the hydrogel. |
申请公布号 |
US8287906(B2) |
申请公布日期 |
2012.10.16 |
申请号 |
US20090545004 |
申请日期 |
2009.08.20 |
申请人 |
KURISAWA MOTOICHI;WANG LI SHAN;CHUNG JOO EUN;LEE FAN;AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH |
发明人 |
KURISAWA MOTOICHI;WANG LI SHAN;CHUNG JOO EUN;LEE FAN |
分类号 |
A61K9/10;C12N5/02;C12P1/00;C12Q1/28 |
主分类号 |
A61K9/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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