发明名称 |
METHODS AND MATERIALS FOR REDUCING SUPRESSION OF IMMUNE FUNCTION |
摘要 |
<p>This document provides methods and materials involved in reducing suppression of immune function in mammals. For example, methods and materials for (a) identifying a mammal as having an elevated level of CD14+/DR- cells (e.g., CD14+/DR- monocytes) and (b) administering RU486 (mifepristone; or drugs with a similar functional profile) to the identified mammal under conditions that change the ratio of CD14+/HLA-DR- cells to CD14+/HLA-DR+ cells as well as methods and materials for (a) identifying a mammal as being likely to experience an elevated level of CD14+/DR- cells (e.g., CD14+/DR- monocytes) and (b) administering RU486 (mifepristone; or drugs with a similar functional profile) to the identified mammal under conditions that reduce the degree to which the mammal develops CD14+/DR- cells are provided.</p> |
申请公布号 |
WO2012138857(A2) |
申请公布日期 |
2012.10.11 |
申请号 |
WO2012US32321 |
申请日期 |
2012.04.05 |
申请人 |
MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH;DIETZ, ALLAN B.;BULUR, PEGGY A. |
发明人 |
DIETZ, ALLAN B.;BULUR, PEGGY A. |
分类号 |
A61K31/56;A61K31/5575;A61K31/567;A61P35/00 |
主分类号 |
A61K31/56 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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