发明名称 |
External cavity laser biosensor arrangements |
摘要 |
A label-free biosensor detection arrangement incorporating an external cavity laser (ECL) includes a tunable lasing element (e.g. an antireflection coated laser diode or semiconductor optical amplifier) and a narrow bandwidth resonant reflectance filter as the wavelength-selective element for the tunable lasing element. A sample is deposited on the surface of the resonant reflectance filter containing a biological material. The wavelength emitted by the external cavity laser is continuously tunable by binding interactions between the biological material and the resonant reflectance filter or adsorption of the biological material present in the sample on resonant reflectance filter. The narrow bandwidth resonance reflectance filter can take the form of photonic crystal (PC), a Bragg stack, or a Brag fiber reflection filter. |
申请公布号 |
US2012258549(A1) |
申请公布日期 |
2012.10.11 |
申请号 |
US201213433619 |
申请日期 |
2012.03.29 |
申请人 |
SRU BIOSYSTEMS, INC.;THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS |
发明人 |
LU MENG;GE CHUN;CUNNINGHAM BRIAN T.;SCHULZ STEPHEN |
分类号 |
G01N21/75;G01N21/64 |
主分类号 |
G01N21/75 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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