发明名称 |
BENZODIOXEPINE AND BENZODIOXINE COMPOUNDS THAT INTERACT WITH GLUCOKINASE REGULATORY PROTEIN FOR THE TREATMENT OF DIABETES |
摘要 |
The present invention relates to compounds of formula I or II, or pharmaceutically acceptable salts thereof, that interact with glucokinase regulatory protein. In addition, the present invention relates to methods of treating type 2 diabetes, and other diseases and/or conditions where glucokinase regulatory protein is involved using the compounds, or pharmaceutically acceptable salts thereof, and pharmaceutical compositions that contain the compounds, or pharmaceutically acceptable salts thereof.
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申请公布号 |
CA2832286(A1) |
申请公布日期 |
2012.10.11 |
申请号 |
CA20122832286 |
申请日期 |
2012.04.04 |
申请人 |
AMGEN INC. |
发明人 |
BARTBERGER, MICHAEL D.;CROGHAN, MICHAEL D.;FOTSCH, CHRISTOPHER H.;NORMAN, MARK H.;PENNINGTON, LEWIS D.;REICHELT, ANDREAS;ST. JEAN, DAVID J., JR.;TEGLEY, CHRISTOPHER M. |
分类号 |
C07D321/10;A61K31/357;A61K31/381;A61K31/422;C07D333/58;C07D407/12;C07D407/14;C07D409/04;C07D409/12;C07D409/14;C07D413/12;C07D417/12;C07D417/14;C07D495/04;C07D513/04 |
主分类号 |
C07D321/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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