SMALL MOLECULE RNASE INHIBITORS AND METHODS OF USE
摘要
Small molecule inhibitors of bacterial ribonuclease (e.g., RnpA) and methods for their synthesis and use are described herein. The methods of using the compounds include treating and preventing microbial infections and inhibiting bacterial ribonuclease. Also described herein are methods of identifying compounds for treating or preventing a microbial infection.
申请公布号
WO2012103295(A3)
申请公布日期
2012.10.11
申请号
WO2012US22662
申请日期
2012.01.26
申请人
UNIVERSITY OF ROCHESTER;BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA;DUNMAN, PAUL M.;OLSON, PATRICK D.