发明名称 COMPOSITION FOR EXTERNAL APPLICATION
摘要 <p>Provided is a composition for external application, which comprises pyrroloquinolinequinone (PQQ) or a pharmaceutically acceptable salt thereof and a surfactant and has a pH value of 4-6. When a surfactant is added to a composition containing PQQ or a salt thereof, the stability of PQQ or the salt thereof is deteriorated significantly. The storage stability of PQQ or a salt thereof in a composition comprising PQQ or the salt thereof and a surfactant can be improved by adjusting the pH value of the composition to 4-6.</p>
申请公布号 WO2012137932(A1) 申请公布日期 2012.10.11
申请号 WO2012JP59549 申请日期 2012.04.06
申请人 ROHTO PHARMACEUTICAL CO., LTD.;FUKUSHIMA, KAZUHIRO 发明人 FUKUSHIMA, KAZUHIRO
分类号 A61K8/49;A61K8/86;A61K31/437;A61K47/10;A61Q1/14;A61Q19/00;C07D471/04 主分类号 A61K8/49
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