发明名称 |
I-CREI MEGANUCLEASE VARIANTS WITH MODIFIED SPECIFICITY, METHOD OF PREPARATION AND USES THEREOF |
摘要 |
Method of preparing I-CreI meganuclease variants having a modified cleavage specificity, variants obtainable by said method and their applications either for cleaving new DNA target or for genetic engineering and genome engineering for non-therapeutic purposes. Nucleic acids encoding said variants, expression cassettes comprising said nucleic acids, vectors comprising said expression cassettes, cells or organisms, plants or animals except humans, transformed by said vectors. |
申请公布号 |
US2012258537(A1) |
申请公布日期 |
2012.10.11 |
申请号 |
US201213422902 |
申请日期 |
2012.03.16 |
申请人 |
DUCHATEAU PHILIPPE;PAQUES FREDERIC;CELLECTIS |
发明人 |
DUCHATEAU PHILIPPE;PAQUES FREDERIC |
分类号 |
C12N9/16;A01H5/00;A01K67/027;C12N1/19;C12N1/21;C12N15/55;C12N15/63 |
主分类号 |
C12N9/16 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|