发明名称 |
Methods and/or Use of Oligonucleotide Conjugates for Assays and Microscopy/Imaging Detections |
摘要 |
The present disclosure is directed to methods and/or uses of oligonucleotide conjugates for assays and microscopy/imaging detections and related systems and/or kits. Certain methods are directed to a method for detecting one or more biological targets of a sample in a detection assay, comprising: providing a molecular probe, comprising a binding moiety and an oligonucleotide sequence, to a sample comprising one or more biological targets; binding the one or more biological targets with the binding moiety; providing a detectable component to the sample, wherein the detectable component comprises a signal generating moiety conjugated to an oligonucleotide sequence complementary to the oligonucleotide sequence of the molecular probe; hydridizing the oligonucleotide sequence of the target-bound molecular probe to the detectable component; and detecting a signal generated from the hydridized detectable component. Various other embodiments, applications etc. are disclosed herein.
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申请公布号 |
US2012258881(A1) |
申请公布日期 |
2012.10.11 |
申请号 |
US201113302890 |
申请日期 |
2011.11.22 |
申请人 |
SCHWARTZ DAVID A.;WILLIAMS JIMMY;ZHAO XINFANG;ZHAO CHUNFANG;BUSA WILLIAM B.;KRON STEPHEN J.;FLOR AMY CATHERINE;THE UNIVERSITY OF CHICAGO;SOLULINK, INC. |
发明人 |
SCHWARTZ DAVID A.;WILLIAMS JIMMY;ZHAO XINFANG;ZHAO CHUNFANG;BUSA WILLIAM B.;KRON STEPHEN J.;FLOR AMY CATHERINE |
分类号 |
C12Q1/68;B82Y15/00;C12Q1/70;C40B30/04;G01N21/00;G01N21/25;G01N21/47;G01N21/59;G01N21/64;G01N21/65;G01N21/66;G01N21/76;G01N24/00;G01N27/72 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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