发明名称 |
RGD-BINDING COMPOUNDS AND METHODS OF USE |
摘要 |
Provided herein are compositions and methods for preventing and treating diseases and risk factors associated with metabolic syndrome by targeting the RGD-binding site of selected intra- and extracellular proteins. Exemplary compositions include RGD-polyphenol conjugates via an ester linkage; polyphenol polymer conjugated to RGD analogs or mimetics; and RGD polymer conjugates linked to polyphenol. |
申请公布号 |
US2012258069(A1) |
申请公布日期 |
2012.10.11 |
申请号 |
US201113156047 |
申请日期 |
2011.06.08 |
申请人 |
ALEXANDER-BRIDGES MARIA;MOUSA SHAKER A.;DAVIS PAUL J. |
发明人 |
ALEXANDER-BRIDGES MARIA;MOUSA SHAKER A.;DAVIS PAUL J. |
分类号 |
C08G63/91;A61K47/48;A61P3/00;A61P5/48;C12Q1/68;C40B30/04;C40B30/06;G01N33/566 |
主分类号 |
C08G63/91 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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