| 发明名称 |
TRI-, TETRA-SUBSTITUTED-3-AMINOPYRROLIDINE DERIVATIVE |
| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a quinolone-based synthetic antibacterial medicine and a therapeutic agent for infectious diseases exhibiting wide and strong antibacterial activity against gram-positive bacteria and gram-negative bacteria and having high safety. <P>SOLUTION: The compound is represented by formula (19). In the formula: R<SP POS="POST">3</SP>is a 1-6C alkyl group which may have a halogen atom as a substituent; R<SP POS="POST">4</SP>and R<SP POS="POST">5</SP>together form a cyclopropane ring including the carbon atom shared by them to form a spirocyclic structure with a pyrrolidine ring; R<SP POS="POST">6</SP>and R<SP POS="POST">7</SP>are each a hydrogen atom; and R<SP POS="POST">11</SP>and R<SP POS="POST">21</SP>are each independently a hydrogen atom or an amino-protecting group. <P>COPYRIGHT: (C)2013,JPO&INPIT |
| 申请公布号 |
JP2012193195(A) |
申请公布日期 |
2012.10.11 |
| 申请号 |
JP20120153741 |
申请日期 |
2012.07.09 |
| 申请人 |
DAIICHI SANKYO CO LTD |
发明人 |
TAKAHASHI HISASHI;INAGAKI HIROAKI;KOMORIYA SATOSHI;TAKEMURA MAKOTO;MIYAUCHI RIE |
| 分类号 |
C07D209/54;C07D401/04 |
主分类号 |
C07D209/54 |
| 代理机构 |
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