Breast density is a significant breast cancer risk factor measured from mammograms. Evidence suggests that the spatial variation in mammograms may also be associated with risk. The variation in calibrated mammograms as a breast cancer risk factor was investigated and its relationship with other measures of breast density was explored using full field digital mammography (FFDM) as described herein. A matched case-control analysis was used to assess a spatial variation breast density measure in calibrated FFDM images, normalized for the image acquisition technique variation. The findings indicate the variation measure is a viable automated method for assessing breast density. Insights gained by this work may be used to develop a standard for measuring breast density.
申请公布号
WO2012082994(A3)
申请公布日期
2012.10.11
申请号
WO2011US65091
申请日期
2011.12.15
申请人
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC.;HEINE, JOHN, J.;SELLERS, THOMAS, A.