| 摘要 |
<p>Disclosed is a compound dual-release capsule formulation consisting of bromodihydroartemisinin and a Fe2+ agent, and comprising micropills dissolving in the intestine and micropills for rapid dissolution in the stomach, said micropills dissolving in the intestine consisting of cores of bromodihydroartemisinin and pharmaceutically acceptable excipients enrobed in intestinal-release coating, and said rapid-release micropills dissolving in the stomach consisting of Fe2+ agent and pharmaceutically acceptable excipients. The micropills of intestinal-release bromodihydroartemisinin and the micropills of rapid-release Fe2+ agent are packaged together in gelatin capsules dissolving in the stomach, thus constituting a dual-release formulation.</p> |
