发明名称 STABLE CRYSTALLINE CHLORIDE MODIFICATIONS DOTAP
摘要 FIELD: medicine, pharmaceutics. ^ SUBSTANCE: invention refers to enantiomerically pure (2S)- or (2R)-N,N,N-trimethyl-2,3-bis[[(9Z)-1-oxo-9-octadecenyl]oxy]-1-propanamide chloride (DOTAP chloride) which possess the transfection properties and can find application in medicine and pharmaceutics for intracellular transportation of pharmaceutically active compounds. The invention also refers to a pharmaceutical composition and the use of enantiomerically pure (2S)- or (2R)-DOTAP chloride as an ingredient for preparing drugs. ^ EFFECT: preparing the compounds which possess the transfection properties and can find application in medicine and pharmaceutics for intracellular transportation of pharmaceutically active compounds. ^ 7 cl, 2 tbl, 6 dwg, 6 ex
申请公布号 RU2463291(C2) 申请公布日期 2012.10.10
申请号 RU20070123673 申请日期 2005.11.07
申请人 MERK PATENT GMBKH 发明人 PLACHER MIKHAEHL';KHEDINGER AL'FRED
分类号 A61K9/127;A61K47/18;C07C219/08 主分类号 A61K9/127
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