COMPOSITION FOR PREVENTION AND TREATMENT OF BONE DISEASES COMPRISING EXTRACT OF HOVENIA DULCIS THUNB

摘要

PURPOSE: A composition containing Hoveniadulcis Thunb. extract is provided to effectively treat osteroporosis and related diseases without side effects. CONSTITUTION: A pharmaceutical composition for preventing and treating bone diseases contains Hoveniadulcis Thunb. extract as an active ingredient. The bone diseases are osteroporosis, osteomalacia, racket, or metabolic bone diseases. The extract promotes bone formation by Wnt/beta-catechin signal transduction. The dose of the extract is 0.1-10 g/kg. A food composition for relieving and treating bone diseases contains Hoveniadulcis Thunb. extract as an active ingredient. [Reference numerals] (AA) Relative reporter activity(%); (BB) Control; (CC) Hoveniadulcis Thunb. extract; (DD) HEK-TOP