发明名称 |
DELIVERY OF MRNA FOR THE AUGMENTATION OF PROTEINS AND ENZYMES IN HUMAN GENETIC DISEASES |
摘要 |
Disclosed herein are compositions and methods of modulating the expression of gene or the production of a protein by transfecting target cells with nucleic acids. The compositions disclosed herein demonstrate a high transfection efficacy and are capable of ameliorating diseases associated with protein or enzyme deficiencies. |
申请公布号 |
EP2506857(A1) |
申请公布日期 |
2012.10.10 |
申请号 |
EP20100835016 |
申请日期 |
2010.11.30 |
申请人 |
SHIRE HUMAN GENETIC THERAPIES |
发明人 |
GUILD, BRAYDON, CHARLES;DEROSA, FRANK;HEARTLEIN, MICHAEL;CONCINO, MICHAEL |
分类号 |
A61K9/127;A61K31/7105;A61K48/00;C07H21/02 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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