发明名称 Inhibitors of TGF-R signaling for treatment of CNS disorders
摘要 The present invention relates to the use of oligonucleotides for the preparation of a pharmaceutical composition for the prevention or treatment of a disease, wherein neurogenesis and/or neuroregeneration has a beneficial effect, in particular a disease like Morbus Alzheimer, Morbus Parkinson, Lewy Body Dementia, Amyotrophic Lateral Sclerosis, Spinocerebellar Atrophies, Creutzfeldt Jakob Disease, Frontemporal Dementia, Morbus Pick, AIDS Dementia Complex, Vascular Dementia, Progressive Supranuclear Palsy, Corticobasal Degeneration, Multisystem-Atrophy, Hallervorden Spatz Disease, Huntington's disease, Stroke, Traumatic Brain and spinal cord Injury, Retinitis Pigmentosa, Macular Degeneration, Glaucoma, Cochlea Degeneration, Depression, Schizophrenia, Multiple Sclerosis, and developmental neurodegeneration.
申请公布号 US8283334(B2) 申请公布日期 2012.10.09
申请号 US201113028035 申请日期 2011.02.15
申请人 BOGDAHN ULRICH;AIGNER LUDWIG;WACHS FRANK-PETER;WINNER BEATE;WINKLER JURGEN 发明人 BOGDAHN ULRICH;AIGNER LUDWIG;WACHS FRANK-PETER;WINNER BEATE;WINKLER JURGEN
分类号 A61K31/70;A61K38/00;C07H21/02;C07H21/04;C07K14/71;C12N15/113 主分类号 A61K31/70
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