发明名称 |
COMPOSITIONS AND METHODS TO IMMUNIZE AGAINST HEPATITIS C VIRUS |
摘要 |
Compositions comprising viral antigens and antigenic peptides corresponding to or derived from Hepatitis C virus (HCV) proteins or fragments thereof, fused to heavy and/or light chain of antibodies, or fragments thereof specific for dendritic cells (DCs) are described herein. Included herein are immunostimulatory compositions (HCV vaccines, HCV antigen presenting dendritic cells, etc.) and methods for increasing effectiveness of HCV antigen presentation by an antigen presenting cell, for a treatment, a prophylaxis or a combination thereof against hepatitis C in a human subject, and methods of providing immunostimulation by activation of one or more dendritic cells, methods to treat or prevent hepatitis C. |
申请公布号 |
CA2831294(A1) |
申请公布日期 |
2012.10.04 |
申请号 |
CA20122831294 |
申请日期 |
2012.03.26 |
申请人 |
BAYLOR RESEARCH INSTITUTE;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) |
发明人 |
DUTARTRE, HELENE;LEVY, YVES;BANCHEREAU, JACQUES F.;ZURAWSKI, GERARD |
分类号 |
A61K39/395;A61K39/29;A61P31/12;A61P37/04;C07K16/46;C12N5/0784 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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