发明名称 |
BI-FUNCTIONAL SHRNA TARGETING STATHMIN 1 AND USES THEREOF |
摘要 |
The present invention includes bifunctional shRNAs capable of reducing an expression of a Stathmin 1 gene; wherein at least one target site sequence of the bifunctional RNA molecule is located within the Stathmin 1 gene, wherein the bifunctional RNA molecule is capable of activating a cleavage-dependent and a cleavage-independent RNA-induced silencing complex for reducing the expression level of Stathmin 1.
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申请公布号 |
US2012251617(A1) |
申请公布日期 |
2012.10.04 |
申请号 |
US201213410130 |
申请日期 |
2012.03.01 |
申请人 |
RAO DONALD;NEMUNAITIS JOHN J.;SENZER NEIL;GRADALIS, INC. |
发明人 |
RAO DONALD;NEMUNAITIS JOHN J.;SENZER NEIL |
分类号 |
A61K31/7105;A61K9/127;A61P35/00;C07H21/02;C12N15/63;C12N15/85 |
主分类号 |
A61K31/7105 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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