RADIOLABELLED FLUMAZENIL DERIVATIVES

摘要

A novel 18F- labelled compound suitable for use as a PET tracer for imaging GABA receptors is provided as well as a precursor compound for use in its synthesis and methods for its preparation. Also disclosed herein is an in vivo imaging method comprising administration of said 18F- labelled compound, which finds use in the diagnosis of conditions in which expression of the GABAA receptor is abnormal, or in the monitoring of such conditions.