PROCESS FOR PREPARING OXYCODONE HYDROCHLORIDE HAVING LESS THAN 25 ppm 14-HYDROXYCODEINONE

摘要

PROBLEM TO BE SOLVED: To provide a process for preparing an oxycodone hydrochloride composition having less impurities.

SOLUTION: The process for preparing the oxycodone hydrochloride composition having less than 25 ppm 14-hydroxycodeinone includes hydrogenating, in a solvent, the oxycodone hydrochloride composition having at least less than 100 ppm 14-hydroxycodeinone.

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