SUBSTITUTED 3-(1H-BENZO{D}IMIDAZOL-2-YL)-1H-INDAZOLE-ANALOGS AS INHIBITORS OF THE PDK1 KINASE
摘要
<p>In one aspect, the invention relates to substituted 3-(lH-benzo[d]imidazol-2-yl)-lH- indazole analogs, derivatives thereof, and related compounds, which are useful as inhibitors of the PDK1 kinase; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds and compositions for treating disorders associated with dysfunction of the PDK1 kinase. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.</p>
申请公布号
WO2012135799(A1)
申请公布日期
2012.10.04
申请号
WO2012US31767
申请日期
2012.03.31
申请人
UNIVERSITY OF UTAH RESEARCH FOUNDATION;BEARSS, DAVID, J.;VANKAYALAPATI, HARIPRASAD;SORNA, VENKATASWAMY;WARNER, STEVEN, L.;SHARMA, SUNIL