Administration of TH-302 or another hypoxia activated prodrug in combination with a pharmacological agent that down-regulates or inhibits homology directed repair (HDR) is useful for treating cancer.
申请公布号
WO2012135757(A2)
申请公布日期
2012.10.04
申请号
WO2012US31677
申请日期
2012.03.30
申请人
THRESHOLD PHARMACEUTICALS, INC.;HART, CHARLES;MATTEUCCI, MARK;CURD, JOHN