PURIFICATION OF TRIPHOSPHORYLATED OLIGONUCLEOTIDES USING CAPTURE TAGS
摘要
The present invention relates to a method of preparing triphosphate-modified oligonucleotides using a capture tag. The method allows the synthesis and purification of triphosphate-modified oligonucleotides in high yield and purity suitable for pharmaceutical applications.
申请公布号
WO2012130886(A1)
申请公布日期
2012.10.04
申请号
WO2012EP55520
申请日期
2012.03.28
申请人
RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAET BONN;LUDWIG, JANOS;GOLDECK, MARION;SPROAT, BRIAN
