发明名称 |
Stable bortezomib formulations |
摘要 |
<p>Multi-dose formulations for bortezomib are presented in which bortezomib has significantly improved stability. Especially preferred formulations include those in which bortezomib is in a liquid form suitable for injection, wherein the solvent system predominantly comprises propylene glycol. In other preferred aspects, bortezomib is present as a Lewis donor-acceptor complex with a hetero-bifunctional Lewis base.</p> |
申请公布号 |
AU2011227083(A1) |
申请公布日期 |
2012.10.04 |
申请号 |
AU20110227083 |
申请日期 |
2011.03.18 |
申请人 |
INNOPHARMA, INC. |
发明人 |
SOPPIMATH, KUMARESH;PEJAVER, SATISH;PATEL, KANAIYALAL R.;DASARADHI, LAKKARAJU;SODUM, RAMA;DESU, HARI;PURI, NAVNEET |
分类号 |
A61K31/19;A61K9/08;A61K38/05;A61K47/30 |
主分类号 |
A61K31/19 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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