发明名称 |
METHODS OF DIAGNOSING ULCERATIVE COLITIS AND CROHN'S DISEASE |
摘要 |
The present invention relates to methods of prognosing inflammatory bowel disease (IBD) in an individual by determining the presence of at least one risk genetic variant and/or at least one risk serological marker. In one embodiment, the presence of risk serological marker ANCA is indicative of an aggressive form of ulcerative colitis. In another embodiment, the present invention relates to methods of diagnosing a Crohn's disease subtype in an individual, where the presence of risk variants and serological markers I2, OmpC and/or Cbir1 are indicative of the Crohn's disease subtype.
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申请公布号 |
CA2830351(A1) |
申请公布日期 |
2012.10.04 |
申请号 |
CA20122830351 |
申请日期 |
2012.03.26 |
申请人 |
CEDARS-SINAI MEDICAL CENTER |
发明人 |
TAYLOR, KENT D.;MCGOVERN, DERMOT P.;ROTTER, JEROME I.;TARGAN, STEPHAN R.;HARITUNIANS, TALIN |
分类号 |
C12Q1/68;C40B30/00;G01N33/48 |
主分类号 |
C12Q1/68 |
代理机构 |
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地址 |
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