| 发明名称 |
IL-17 RECEPTOR A ANTIGEN BINDING PROTEINS |
| 摘要 |
The present invention relates to IL-17 Receptor A (IL-17RA or IL-17R) antigen binding proteins, such as antibodies, polynucleotide sequences encoding said antigen binding proteins, and compositions and methods for diagnosing and treating diseases mediated by IL-17 Receptor A activation by one or more IL-17 ligands. The present invention relates to the identification of neutralizing determinants on IL-17 Receptor A (IL-17RA or IL-17R) and antibodies that bind thereto. Aspects of the invention also include antibodies that compete for binding with the IL-17RA neutralizing antibodies described herein.
|
| 申请公布号 |
US2012251547(A1) |
申请公布日期 |
2012.10.04 |
| 申请号 |
US201213472074 |
申请日期 |
2012.05.15 |
| 申请人 |
TOCKER JOEL;PESCHON JACQUES J.;FITZPATRICK DAVID;SMOTHERS JAMES F.;MEHLIN CHRISTOPHER;LIM AI CHING;AMGEN, INC. |
发明人 |
TOCKER JOEL;PESCHON JACQUES J.;FITZPATRICK DAVID;SMOTHERS JAMES F.;MEHLIN CHRISTOPHER;LIM AI CHING |
| 分类号 |
C07K16/28;A61K39/395;A61P1/00;A61P1/04;A61P3/10;A61P5/16;A61P9/10;A61P11/00;A61P11/06;A61P17/00;A61P17/06;A61P19/02;A61P19/04;A61P19/08;A61P21/04;A61P25/00;A61P29/00;A61P31/14;A61P37/00;A61P37/06;C12N15/13;C12N15/85 |
主分类号 |
C07K16/28 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
