| 发明名称 |
TREATMENT OF SIRTUIN (SIRT) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO A SIRTUIN (SIRT) |
| 摘要 |
The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of a Sirtuin (SIRT), in particular, by targeting natural antisense polynucleotides of a Sirtuin (SIRT). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of Sirtuins (SIRT)s.
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| 申请公布号 |
US2012252869(A1) |
申请公布日期 |
2012.10.04 |
| 申请号 |
US201013386057 |
申请日期 |
2010.07.23 |
| 申请人 |
COLLARD JOSEPH;KHORKOVA SHERMAN OLGA;OPKO CURNA, LLC |
发明人 |
COLLARD JOSEPH;KHORKOVA SHERMAN OLGA |
| 分类号 |
A61K31/7088;A61K38/14;A61P1/00;A61P1/04;A61P1/16;A61P3/00;A61P3/04;A61P3/06;A61P3/10;A61P7/00;A61P9/00;A61P9/10;A61P11/00;A61P13/00;A61P17/00;A61P19/00;A61P19/02;A61P19/08;A61P19/10;A61P21/00;A61P25/00;A61P25/16;A61P25/28;A61P27/02;A61P29/00;A61P31/18;A61P35/00;A61P35/02;C07H21/04;C07K9/00;C12N5/071 |
主分类号 |
A61K31/7088 |
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